Long-term use of hydrocodone vs. oxycodone in primary care.

Rebecca Arden Harris,Henry R Kranzler,Kyong-Mi Chang,Chyke A Doubeni,Robert Gross

Drug and Alcohol Dependence（2019）

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摘要

•Hydrocodone and oxycodone are the most prescribed Schedule II opioids.•Equianalgesic opioids are widely assumed to induce similar rates of long-term use.•Hydrocodone had a 9% greater risk of long-term use than oxycodone.•The increased risk was 17% among patients who received more than one prescription.

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关键词

Opioids,Hydrocodone,Oxycodone,Acute back pain,Primary care,Long-term opioid use

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