Long noncoding RNA MIAT promotes the progression of acute myeloid leukemia by negatively regulating miR-495.

Gaoyan Wang,Xuerong Li,Liang Song,Hua Pan,Jian Jiang,Lirong Sun

Leukemia Research（2019）

引用 24|浏览4

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摘要

•MIAT is highly expressed in AML patients than healthy controls.•High MIAT expression can predict poor over survival in AML patients.•MIAT promotes the proliferation and inhibits the apoptosis of AML cells.•MIAT acts as a sponge to negatively regulate miR-495 in AML cells.

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关键词

AML,LncRNA,MIAT,RNCR2,miRNA,BM,FAB,FBS,CCK-8,qRT-PCR,TCGA,HSC,LSCs,CMP,GMP

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