Network connectivity separate from the hypothesized irritative zone correlates with impaired cognition and higher rates of seizure recurrence.

•Maps of networks in patients with temporal lobe epilepsy and was applied in 22 patients•Distribution of epilepsy networks correlated with objective measures of the neuropsychological exam.•Higher connectivity in the contralateral lobe was measured in some patients.•Higher connectivity was found in patients with worse neurocognitive function.