A Retrospective Study Of Fqsrl And Ipl In The Treatment Of Cafe-Au-Lait Macule

Background: The application of fractional Q-switched ruby laser (FQSRL) or intense pulsed light (IPL) on Cafe-au-lait macule (CALM) is rational and the data are lacking.Objective: To evaluate the efficacy and safety of FQSRL and IPL in CALM.Methods: The patients with CALM who were treated with FQSRL or IPL were retrospectively observed from April 2016 to April 2019. The laser/light treatments were conducted at an interval of 3-4 weeks.Results: For FQSRL (N=67), 88.23%, 95.46%, 100% patients achieved >50% improvement by three sessions, four sessions, and more than four sessions of treatment, respectively. A better and better efficacy was shown with the increasing number of sessions (chi(2)=89.51, p<.01). For IPL (N=54), 45% and 87.5% achieved >50% improvement by three sessions and more than four sessions of treatments, respectively. More than four sessions achieved better efficacy than less sessions (p<.01). Under various time-points, FQSRL presented more favorable responses than IPL (p<.05). All the adverse effects were tolerable and acceptable.Conclusions: FQSRL or IPL would be an alternative and safe modality for CAML in Chinese patients.