Interleukin 10 promotes macrophage uptake of HDL and LDL by stimulating fluid-phase endocytosis.
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids（2020）
摘要
•IL-10 induces the uptake of HDL and LDL in macrophages by fluid-phase endocytosis.•IL-10 activates cofilin activity and increases actin filament turnover in macrophages.•IL-10-induced uptake of HDL and LDL by fluid-phase endocytosis may explain, in part, “Disappearing HDL Syndrome”
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关键词
Interleukin 10,High-density lipoprotein,Low-density lipoprotein,Macrophages,Fluid-phase endocytosis
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