Integration of Flow Cytometry and Single Cell Sequencing.
Trends in Biotechnology(2020)
摘要
Integrating cytometric analysis of cells, mitochondria, and other polynucleotide-containing biological particles with high-throughput single particle sequencing would provide an ultimate bioanalytical tool, simultaneously assessing phenotype, functionality, genome, and transcriptome of each particle in a large population. Here, we describe how such integration could be performed by adapting existing, well-established technologies.
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关键词
single-cell sequencing,cytometry,Drop-seq,CITE-seq,REAP-seq
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