Jump ahead with a twist: DNA acrobatics drive transposition forward

Current Opinion in Structural Biology(2019)

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摘要
•Transposition reactions are ubiquitous and involve complex DNA rearrangements.•Transposase-DNA complex structures reveal key mechanistic principles.•DNA bending, unwinding and melting promote all steps of transposase function.•DNA distortions serve universal roles in transposition and related cellular processes.
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