Radiomics of Gastrointestinal Stromal Tumors; Risk Classification Based on Computed Tomography Images – A Pilot Study

Background: Gastrointestinal stromal tumors (GISTs) are rare mesenchymal tumors of the gastrointestinal (GI) tract. The size, the presence of mutations found in the c-KIT gene and the mitotic index are used to determine the prognostic group and to direct systemic treatment choices. This study evaluates the use of radiomics, a technique which uses algorithms to predict clinical outcomes from medical imaging features, for diagnosing and predicting the c-KIT mutational status of GIST.