A Piezogravimetric Sensor Platform for Sensitive Detection of Lead (II) Ions in Water Based on Calix[4]resorcinarene Macrocycles: Synthesis, Characterization and Detection

•Novel enantiomeric calixresorcinarenes were synthesized and characterized.•The employment of a newly developed sensitive (QCM-I) for metal ions detection tests.•Calixr-coated QCM resonators effectively functioned as chemical sensors.•The system produced wide linear ranges, adequate sensitivities as well as low (LOD).