The prognostic significance of BCR-1 and BCR-3 isoforms of PML-RARA and FLT3-ITD in patients with acute promyelocytic leukemia

Clinical Lymphoma Myeloma and Leukemia(2020)

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摘要
Age is an independent prognostic factor for APL. bcr-3 is significantly associated with FLT3-ITD in adults with APL. DIC and FLT3-ITD are adverse prognostic factors in children with APL. Despite children being at higher risk, outcome is better than in adults.
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关键词
APL,bcr-1,bcr-3,FLT3-ITD,Prognosis
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