PP.27.11: STRUCTURAL AND FUNCTIONAL ALTERATIONS IN CEREBRAL AND MESENTERIC SMALL RESISTANCE ARTERIES FROM CONGENIC LINES FOR A MAJOR STROKE QTL ON RAT CHROMOSOME 1 AFTER HIGH SALT DIET

C. De Ciuceis,C. Rossini,E. Porteri,S. Rubattu, M. Cotugno,R. Stanzione, M. Madonna,C. Rosei, E. La Boria,A. Sarkar,A. Gavazzi,B. Petroboni,M. Volpe,E. Rosei,D. Rizzoni

JOURNAL OF HYPERTENSION（2015）

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摘要

Objective:A quantitative trait locus (QTL) for stroke proneness between the kallikrein (Klk) and Mt1pa markers on rat chromosome 1 was previously identified, and to gain functional insights, congenic strains were constructed by introgressing a selected chromosomal segment from the stroke-prone (SHRs

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