Pharmacogenetic Study of the Central Nervous System in Pediatric Acute Lymphoblastic Leukemia

Judit C. Sagi,Anna Artner,Andrea Kelemen,Balint Egyed, Andrea Rzepiel,Nora Kutszegi,Andras Gezsi,Gabor T. Kovács,Csaba Szalai,Daniel J. Erdelyi,Agnes F. Semsei

Clinical Lymphoma Myeloma and Leukemia（2019）

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摘要

Pediatric acute lymphoblastic leukemia (ALL) has a favorable prognosis thanks to the combined chemotherapy, however, relapsed disease and serious adverse effects caused by the treatment still needs to take in consideration.

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关键词

childhood cancer,genetic polymorphisms,neurotoxicity,ALL,acute lymphoblastic leukemia

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