Production of poly (ε-caprolactone) Antimicrobial Nanofibers by Needleless Alternating Current Electrospinning

The present study is focused on the fabrication of antimicrobial polycaprolactone (PCL) nanofibers using uncommon needleless and collector less alternating current (AC) electrospinning. The PCL polymeric solutions (6 & 12 wt.%) were prepared using 1:1 acetic acid and formic acid. The antimicrobial agent chlorhexidine (CHX) was added to the PCL precursor solution at 1 wt%. The PCL/CHX solutions (6 &12 wt.%) were electrospinnable at the applied AC potential of 25kV and 35kV rms. The surface morphological investigation of PCL/CHX antimicrobial nanofibers confirmed that smooth beadless nanofibers have been obtained. Fiber diameter and viscosity were increasing with respect to PCL/CHX concentrations.