Nivolumab-Induced Celiac-Like Enteropathy In Patient With Metastatic Renal Cell Carcinoma: Case Report And Review Of The Literature

Lucie Duval,Sarah Habes, Thierry Chatellier, Pascale Guerzider,Céline Bossard, Claude Masliah,Isabelle Archambeaud,Yann Touchefeu,Tamara Matysiak‐Budnik

CLINICAL CASE REPORTS（2019）

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摘要

Nivolumab may induce severe celiac-like enteropathy, that may appear very rapidly, after only two injections of nivolumab, and may be successfully treated with corticosteroids. This observation underlines the importance of histological analysis of duodenal biopsies and the necessity to rule out a real celiac disease in patients with nivolumab-induced diarrhea.

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关键词

celiac-like enteropathy, immune-related adverse effects, immunotherapy, nivolumab, PD-1 inhibitors

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