PSIV-19 Dietary spray dried plasma on immune responses of lactating sows and their litters

Abstract This study was conducted to investigate the effects of spray dried plasma (SDP) in lactation diets on immune responses of lactating sows and their litters. A total of 12 lactating sows (227.75 ± 7.50 kg BW; parity = 2.0 ± 0.7) were randomly assigned to 2 dietary treatments in a completely randomized design. The dietary treatments were a typical lactation diet based on corn and soybean meal (CON) and CON supplemented with 1% of SDP (SDP). Sows were fed experimental diets from d 30 before expected farrowing to weaning. Blood Samples were collected from sows on d 0, 3, and 7 after farrowing and randomly selected 2 piglets in each sow on d 3 and 7 after birth. Measurements were serum tumor necrosis factor-α (TNF-α), transforming growth factor-β (TGF-β), C-reactive protein (CRP), cortisol, and immunoglobulin (Ig)G, M, and A from their litters by the enzyme-linked immunosorbent assay. Data were analyzed using the PROC GLM of SAS. Sows fed SDP tended (P < 0.10) to have lower serum TNF-α on d 3 (264.94 vs. 281.96 pg/ml) and d 7 (249.35 vs. 272.15 pg/ml) than sows fed CON. Moreover, SDP tended (P < 0.10) to decrease of serum TGF-β (311.37 vs. 448.07 pg/ml) and cortisol (0.47 vs. 0.55 ng/ml) on d 3 compared with CON. The litters from sows fed SDP tended (P < 0.10) to reduce serum TNF-α (349.87 vs. 423.57 pg/ml), TGF-β (853.49 vs. 980.41 pg/ml), and cortisol (0.62 vs. 1.05 ng/ml) on d 7 than litters from sows fed CON. However, there were no differences on CRP, IgG, IgM, and IgA of sows and their offspring between CON and SDP. In conclusion, supplementation of dietary spray dried plasma in lactation diets may reduce inflammatory responses of sows and their litters.