Postnatal delayed growth impacts cognition but rescues programmed impaired pulmonary vascular development in an IUGR rat model.

Nutrition, Metabolism and Cardiovascular Diseases(2019)

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摘要
•Postnatal delayed growth resulted in cognitive impairment, but rescued pulmonary arteriolar remodeling induced by IUGR.•The rescued pulmonary arteriolar remodeling may be related to an improvement of eNOS expression.•The impaired learning and memory may be related to a failed induction of zif268 and p300.
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关键词
IUGR,Delayed postnatal growth,Cognitive function,Pulmonary arterial hypertension
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