Mapping RNA-chromatin interactions by sequencing with iMARGI

Weixin Wu
Weixin Wu
Zhangming Yan
Zhangming Yan
Tri C Nguyen
Tri C Nguyen
Zhen Bouman Chen
Zhen Bouman Chen

Nature protocols, pp. 3243-3272, 2019.

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Abstract:

RNA-chromatin interactions represent an important aspect of the transcriptional regulation of genes and transposable elements. However, analyses of chromatin-associated RNAs (caRNAs) are often limited to one caRNA at a time. Here, we describe the iMARGI (in situ mapping of RNA-genome interactome) technique, which is used to discover caRNA...More

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