Intermittent treatment with azithromycin and ethambutol for non-cavitary Mycobacterium avium complex pulmonary disease.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY(2020)
摘要
We evaluated the efficacy of intermittent azithromycin and ethambutol therapy for noncavitary Mycobacterium avium complex pulmonary disease (MAC-PD). Twenty-nine (76%) of 38 patients achieved sputum culture conversion after 12 months of treatment, and sputum smear positivity was an independent factor for failure to achieve culture conversion (adjusted odds ratio, 26.7; 95% confidence interval, 2.1 to 339.9; P = 0.011). Intermittent azithromycin and ethambutol may be an optional treatment regimen for noncavitary MAC-PD.
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关键词
macrolide,ethambutol,intermittent therapy,Mycobacterium avium complex
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