Protocol-driven multidetector SPECT/CT: integration of hybrid imaging into the routine workflow of whole-body bone scintigraphy in oncology patients.

•SPECT/CT in bone scintigraphy can be used selectively in a protocol-driven manner for oncology patients.•SPECT/CT reduces equivocal findings compared to planar BS imaging.•SPECT/CT significantly increases reporter confidence in the axial skeleton.•Prospective studies are required to evaluate the impact of SPECT/CT on clinical management.