A novel non-enzymatic glucose electrochemical sensor based on CNF@Ni-Co layered double hydroxide modified glassy carbon electrode

A non-enzymatic glucose electrochemical sensor based on carbon nanofiber coat with nickel‑cobalt layered double hydroxide (CNF@ NiCo LDH) which was made by electrospinning techniques and chemical deposition. The morphology and structural behaviours of the CNF@ NiCo LDH were investigated by scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (XPS). Meanwhile, the electrochemical performances of the nanocomposite modified glassy carbon electrode (GCE) was demonstrated by cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). The presence of NiCo LDH nanosheets on CNFs strongly improved the surface area and that thus enhanced its electrocatalysis efficiency. Meanwhile, the ratio of the Ni to Co was optimized to achieve the best electrocatalytic capability for glucose. The developed sensor exhibited a wide linear range (1–2000 μM), low detection limit (0.03 μM) and high sensitivity (1.47 mA mM−1 cm−2) towards glucose. The excellent results demonstrated that the CNF@ NiCo LDH sensing platform might provide practical applicability and reliability towards human serum detection.