Coordination behavior of organothiophosphate ligands towards trivalent lanthanide complexes and potential use as V-series chemical warfare agent simulants

In order to develop new, low toxicity and readily accessible supramolecular simulants for V-series organophosphorus chemical warfare agents (OP CWAs) a series of organothiophosphate compounds, that are structurally analogous to the V-series OP CWAs, were designed and synthesized. Solution spectroscopic studies (luminescence and UV-vis) into the binding behaviors of these compounds and some organothiophosphate pesticides with the simple model trivalent lanthanide complex [Eu(phen)(2)(NO3)(3)]center dot 3H(2)O were performed and association constants (K-assoc) determined. Binding behaviors of these compounds with other OP CWAs and simulants investigated previously in analogous studies are presented and the implications of this in the context of OP CWA and related chemical sensing are discussed. [GRAPHICS] .