United States Practice Patterns and Comparative Effectiveness of GOG 249 Arms

In 2009, GOG 249 began randomizing women with high risk, early stage uterine carcinoma to whole pelvic radiotherapy (WPRT) or vaginal cuff brachytherapy and chemotherapy (VBT+CT) after definitive surgery. In 2014, initial Results revealed that VBT+CT was not superior to WPRT and had more grade ≥3 acute toxicities. Patterns of care analysis and comparison of overall survival (OS) among women who met criteria for GOG 249 and were treated with similar therapies was performed.