Association of low-dose aspirin use and survival of women with monocytosis in endometrial cancer

Objectives: Tumor-associated macrophages (TAMs) are known to be associated with decreased survival in endometrial cancer. The number of monocytes, progenitors of macrophages, has been shown to be associated with worse survival in endometrial cancer. Given a recent study demonstrating anti-tumor effects with aspirin via TAMs inhibition in other tumor models, this study examined the association of aspirin use on survival among endometrial cancer patients with monocytosis.