AB0847 INCIDENCE RATES OF OSTEOPOROSIS(OP) RISK FACTORS IN A LARGE URBAN LONDON BOROUGH

Background Identification of osteoporosis risk factors(OPRFs) is a necessary part of assessing fracture risk and treating patients with OP. Incidence rates of OPRFs are variably reported in the literature. Patients seen in OP clinics tend to have a higher risk of fractures compared to those managed in primary-care hence the need for closer scrutiny of their OPRFs. In some instances, managing modifiable OPRFs may form the principle part of the patient’s management plan. Objectives We examined the rates of OPRFs in patients attending the Bone Health Clinic at Croydon Health Services NHS Trust. Methods Retrospective review of OP patients seen between February-June 2018 at Purley Memorial Hospital and assessed for presence of OPRFs including: demographics,BMI,early menopause,late menarche,nulliparity,secondary medical conditions,medicines,family history of OP/parental hip fracture,recurrent falls,previous fragility fractures(FFs) and lifestyle OPRFs(smoking,alcohol,low calcium intake,sedentary). Results 201 patients were included. Mean age was 70-years-old(range:37-96), with approximately 9:1 female:male ratio. Mean BMI was 23(normal) with approximately 20% being 16years). Of the 25.5% with early menopause, only 13%(6/46) had been offered HRT. 17% of women were nulliparous. Of the medical conditions, thyroid disease was the most commonly reported(18%) with a third of these being newly diagnosed in clinic. Coeliac was identified in 7.5% with 5% newly diagnosed. 2% had newly diagnosed haematological disorders (MGUS,Myeloma,Lymphoma). Only 8 patients had 2-or-more diagnoses at the same time. Almost 40% had a family history of OP, 19% history of parental hip fracture and 15% had both. The majority 66.7%(134/201) had experienced a previous FF with 36% having suffered 2 or more. 16%(32/201) had experienced recurrent falls. 19% were living sedentarily, 11% currently smoking, 10% drinking 3 or more units of alcohol-per-day and 31% having poor dietary calcium, with 22% having 2 or more of these lifestyle OPRFs. Of the medicines, steroids and PPIs were the most commonly seen. Overall, 73%(147/201) of subjects had at least one modifiable OPRF with over half having 2 or more OPRFs. Conclusion This study identified numerous OPRFs and their incidences. Low BMI( Disclosure of Interests None declared