“On Water” Promoted N-Arylation Reactions using Cu (0)/myo-inositol catalytic system

Qifan Zhou,Fangyu Du,Yuanguang Chen,Yang Fu,Guoliang Chen

Tetrahedron Letters（2019）

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摘要

•Myo-inositol, a cardiovascular medicine, was used as tridentate O-donor ligand for Cu-catalyzed amination reaction in water.•The CN coupling reaction of aryl halides with amines were achieved by Cu powder/myo-inositol catalytic system.•The broad scope of substrates was participated in the coupling.

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关键词

Myo-inositol,N-Arylation,Copper,Water

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