The P300 event-related potential in bipolar disorder: A systematic review and meta-analysis

Masataka Wada,Shin Kurose,Takahiro Miyazaki,Shinichiro Nakajima,Fumi Masuda,Yu Mimura,Hana Nishida,Kamiyu Ogyu,Sakiko Tsugawa, Yuuki Mashima,Eric Plitman,M. Mallar Chakravarty,Masaru Mimura,Yoshihiro Noda

Journal of Affective Disorders（2019）

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摘要

•P300 reflected variety of cognitive dysfunction in patients with BD.•BD had reduced P3a/P3b amplitude and delayed P3b latency with any paradigm.•Phase, psychosis, and diagnostic subcategories did not affect P300 abnormalities.•P300 abnormalities may be a trait marker rather than a state marker of BD.

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关键词

Bipolar disorder,Cognition,Electrophysiology,Biological markers,EEG/Event-related potentials

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