C-H Activation/Metalation Approaches for the Synthesis of Indolizine Derivatives
European Journal of Organic Chemistry(2019)
摘要
The C-H borylation of indolizines has not previously been reported. In this communication, we describe our preliminary efforts to apply this chemistry to this scaffold and contrast this approach to directed metalation. Through these methodologies, it was possible obtain a library of substituted indolizines functionalized on both the pyridinic and pyrrole rings.
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关键词
C–H borylation,Metalation,Indolizines,Cross-coupling,Heterocycles
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