Assessing circadian rhythms and entrainment via intracranial temperature after severe head trauma.

Biomedical Signal Processing and Control(2019)

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摘要
•Intracranial temperature data can be used to infer circadian rhythms.•Circadian rhythmicity improves with good outcomes and declines with bad outcomes.•Circadian phase regulates in subjects with good outcomes.•A robust two-stage Kalman filter can be used to extrapolate missing data.
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关键词
Nonlinear estimation,Circadian rhythms,Traumatic brain injury
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