A multidimensional nomogram combining overall stage, dose volume histogram parameters and radiomics to predict progression-free survival in patients with locoregionally advanced nasopharyngeal carcinoma.

•Radiomic signatures of regional lymph node (RSnd), Dose Volume Histogram signature reflecting planning score (PS), and TNM stage were independent predictors for PFS.•The nomogram integrating the RSnd, PS and TNM stage can accurately predict 3-year and 5-year PFS.•Subgroup analysis showed Epstein–Barr virus DNA status improved the predictive power of the nomogram.•The nomogram can successfully classify patients into low- and high-risk groups, with significantly different PFS.