VWF, CXCL8 and IL6 might be potential druggable genes for acute coronary syndrome (ACS)

Jinxia Gu, Hong Zhu,Dayong Zhu,Ming Li,Mochao Xiao,Dongxia Yan, Shaohui Shen

Computational Biology and Chemistry（2019）

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摘要

•IL6 and VEGFA played major roles in ACS.•Hsa-miR-29 and hsa-miR-1 might be associated with ACS progression.•NFIC, NFKB1 and RELA might be critical transcription factors related to ACS.•VWF, CXCL8 and IL6 might be potential druggable genes for ACS therapy.

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关键词

Acute coronary syndrome,Differentially expressed genes,Functional analysis,Protein-protein interaction network,Regulatory network

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