Evaluation of frequency-selective non-linear blending technique on brain CT in postoperative children with Moyamoya disease

•The frequency-selective non-linear blending (BC) technique can improve tissue contrast between the gray matter and white matter with maintaining overall image quality (BC vs. non-enhanced brain CT; 3.9±1.0 vs. 1.8±0.6, P<0.001).•The diagnostic accuracy of the non-enhanced brain CT and post-processed brain CT images using BC techniques were 63.6% (21/33) and 69.7% (23/33) without significant diagnostic accuracy improvement (P=0.219).•However, the post-processed BC technique may be used to identify brain ischemic changes in a subcortical punctate lesion of postoperative pediatric moyamoya patients by improving contrast-to-noise of the infarct lesion.