Antigenic Variation of Avian Influenza A(H5N6) Viruses, Guangdong Province, China, 2014-2018.

Ru Bai,Reina S Sikkema,Cong Rong Li,Bas B Oude Munnink,Jie Wu,Lirong Zou,Yi Jing,Jing Lu,Runyu Yuan,Ming Liao,Marion P G Koopmans,Chang-Wen Ke

EMERGING INFECTIOUS DISEASES（2019）

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摘要

Market surveillance showed continuing circulation of avian influenza A(H5N6) virus in live poultry markets in Guangdong Province in 2017, despite compulsory vaccination for avian influenza A(H5Nx) and A(H7N9). We analyzed H5N6 viruses from 2014-2018 from Guangdong Province, revealing antigenic drift and decreased antibody response against the vaccine strain in vaccinated chickens.

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关键词

Antigenic variation,China,Guangdong Province,H5N6,avian influenza,chickens,live poultry markets,poultry,viruses,zoonoses

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