TGFβ enhances tissue formation by passaged nucleus pulposus cells in vitro

Sajjad Ashraf
Sajjad Ashraf
Kenny Chatoor
Kenny Chatoor
Jasmine Chong
Jasmine Chong

Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2019.

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Keywords:
Notochord cellsNucleus pulpous cellsTGFβTissue engineering

Abstract:

The nucleus pulposus (NP) is composed of NP and notochord cell. It is a paucicellular tissue and if it is to be used as a source of cells for tissue engineering the cell number will have to be expanded by cell passaging. The hypothesis of this study is that passaged NP and notochordal cells grown in 3D culture in the presence of TGFβ will...More

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