The association between maternal occupation and down syndrome: A report from the national Down syndrome project.

Colleen Keen,Jessica Ezzell Hunter,Emily Graves Allen,Carissa Rocheleau,Martha Waters,Stephanie L Sherman

International Journal of Hygiene and Environmental Health（2020）

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摘要

•Several occupation classes had greater odds of chromosome 21 nondisjunction (NDJ).•Food Preparation and Serving Related occupations had increased odds of Meiosis I NDJ.•Life, Physical and Social Science occupations had increased odds of Meiosis I NDJ.•Production Occupations had greater odds of Meiosis II NDJ.•Meiosis I nondisjunction was associated with solvent exposure among Production Work.

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关键词

Chromosome 21 nondisjunction,Down syndrome,Occupational exposure,Exposure assessment,Maternal occupation,National down syndrome project

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