Compound K attenuated hepatectomy-induced post-operative cognitive dysfunction in aged mice via LXRα activation.

Qifang Liu,Lidan Liu,Hongmei Liu,Jingjing Jiang,Shanbin Guo,Cong Wang,Yi Jia,Yue Tian

Biomedicine & Pharmacotherapy（2019）

引用 8|浏览5

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摘要

•Compound K could attenuate POCD caused by partial hepatectomy in mice.•LXRα pathway is a potential new therapeutic target for POCD.•Hippocampus inflammation is more important than systemic inflammation in POCD.

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关键词

Compound K,Inflammation,Liver X receptor,Post-operative cognitive dysfunction

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