Different Pharmacological Properties of GLUT9a and GLUT9b: Potential Implications in Preeclampsia.

Benjamin P Lüscher,Daniel V Surbek,Benjamin Clémençon,Xiao Huang,Christiane Albrecht,Camilla Marini,Matthias A Hediger,Marc U Baumann

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology（2019）

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摘要

To the best of our knowledge, this is the first study showing that the N-terminal domain of hGLUT9a has a unique regulatory function and the potential to interact with small negatively charged ions like iodide. These findings may have significant implications in our understanding of hyperuricemia-associated diseases, specifically during pregnancy.

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关键词

Electrophysiology,Glucose transporter type 9 (GLUT9),Iodine,Uric acid,Uric acid transport

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