Interleukin-1 Alpha Polymorphisms Are Associated With Body Mass Index in Male But Not in Female Adolescents.

Francisco Mendoza-Carrera,Guadalupe Ramírez-López, Luis Eduardo Hernández-Ramos,Caridad Leal-Cortés,Eliseo Portilla-de-Buen,Xochitl H Castro-Martínez,Anna Gabriela Castro Martínez,Andrés López-Quintero,Silvia E Flores-Martínez,José Sánchez-Corona

Archives of Medical Research（2019）

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摘要

Some MetS parameters seem to be influenced by variations in the IL-1 gene cluster in Mexican adolescents. These variations may confer risk for metabolic alterations from early ages, and and these risks may be different when variables such as sex are considered. Strategies leading to generate protective behaviors could be designed to take into account specific variations in the IL-1 gene cluster and biological conditions such as sex.

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关键词

Polymorphism,Haplotypes,Mexico,Metabolic syndrome,Linkage disequilibrium

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