Inter-manufacturer comparison of automated immunoassays for the measurement of soluble FMS-like tyrosine kinase-1 and placental growth factor.

Yvonne Kwun Yue Cheng,Liona Chiu Yee Poon,Andrew Shennan,Tak Yeung Leung,Daljit Singh Sahota

Pregnancy Hypertension（2019）

引用 15|浏览24

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摘要

•Rule-in/rule-out decision levels are manufacturer specific and not interchangeable.•Elecsys® PlGF and sFlt-1 not reportable in 0.6% samples due to assay interference.•BRAHMS sFlt-1:PlGF ratio equivalent to Elecsys® PE rule out ratio of 38 is 55.•BRAHMS sFlt-1:PlGF ratio equivalent to Elecsys® PE rule in ratio of 110 is 188.

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关键词

Immunoassay,Placental growth factor (PlGF),Soluble FMS-like tyrosine kinase 1 (sFlt-1),SFlt-1:PlGF ratio,Pre-eclampsia,Hypertensive disorders

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