Functional circuitry of neuro-immune communication in the mesenteric lymph node and spleen.
Brain, Behavior, and Immunity(2019)
摘要
•Mesenteric lymph nodes and spleen are innervated by the sympathetic nervous system.•This innervation can be selective activated.•Selective neuronal activation significantly reduces pro-inflammatory cytokine expression.
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关键词
Neuroimmunology,Cholinergic anti-inflammatory pathway,Vagal nerve stimulation,Peripheral optogenetics
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