Functional circuitry of neuro-immune communication in the mesenteric lymph node and spleen.

Brain, Behavior, and Immunity(2019)

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摘要
•Mesenteric lymph nodes and spleen are innervated by the sympathetic nervous system.•This innervation can be selective activated.•Selective neuronal activation significantly reduces pro-inflammatory cytokine expression.
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关键词
Neuroimmunology,Cholinergic anti-inflammatory pathway,Vagal nerve stimulation,Peripheral optogenetics
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