Enhanced neuronal activity in mouse motor cortex with microbubbles' oscillations by transcranial focused ultrasound stimulation.

Zhiwei Cui,Dapeng Li,Yang Feng,Tianqi Xu,Shan Wu, Yibao Li,Ayache Bouakaz,Mingxi Wan,Siyuan Zhang

Ultrasonics Sonochemistry（2019）

引用 25|浏览6

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摘要

•Introducing MBs increased the success rate of motor response to US stimulation.•US stimulation with MBs increased c-fos expression, a neuronal activity marker.•Enhanced neuronal activity induced by MBs is independent of BBB opening.•US stimulation with MBs don’t result in morphological or cellular-level damages.

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关键词

Ultrasound stimulation,Microbubbles,Motor response,c-fos,Neuronal activity

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