Effect of pituitary adenylate cyclase-activating polypeptide-27 on cerebral hemodynamics in healthy volunteers: a 3T MRI study.

Hashmat Ghanizada,Mohammad Al-Mahdi Al-Karagholi,Nanna Arngrim,Mustafa Ghanizada,Henrik Bo Wiberg Larsson,Faisal Mohammad Amin,Messoud Ashina

Peptides（2019）

引用 19|浏览5

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摘要

•PACAP-27 provokes more headache in healthy volunteers compared to placebo.•PACAP-27 causes prolonged dilatation of middle meningeal artery and slightly constricts middle cerebral artery.•PACAP isoforms dilate middle meningeal artery with significantly different magnitude.

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关键词

Headache,Arterial dilation,PACAP receptors,PACAP27,PACAP38

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