Mathematical model of thrombin generation and bleeding phenotype in Amish carriers of Factor IX:C deficiency vs. controls.

S Gupta,M C Bravo,M Heiman,C Nakar,K Brummel-Ziedins,C H Miller, A Shapiro

Thrombosis Research（2019）

引用 3|浏览15

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摘要

•Amish Carriers had lower FIX:C, VWF:Ag and TAFI vs. controls but a similar mean bleeding score.•Amish Carriers demonstrated lower TG parameters on mathematical models vs. controls.•Amish Carriers with FIX:C ≤ 50% had lower TG curves vs. FIX:C > 50% but similar BS.

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关键词

Carriers,Hemophilia B,Bleeding scores,Mathematical model,Thrombin generation

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