Programmed cell death 1 (PD-1) targeting in patients with advanced osteosarcomas: results from the PEMBROSARC study.

A Le Cesne,P Marec-Berard,J-Y Blay,N Gaspar,F Bertucci,N Penel,E Bompas,S Cousin,M Toulmonde, A Bessede,W H Fridman, C Sautes-Fridman,M Kind,F Le Loarer,M Pulido,A Italiano

European Journal of Cancer（2019）

引用 99|浏览44

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摘要

•We report here the results of PD-1 targeting in patients with advanced osteosarcomas.•This therapeutic strategy has only modest activity.•Further studies should explore combination strategies reprogramming the microenvironment.

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关键词

Osteosarcoma,PD-1,Immunotherapy,Pembrolizumab

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