Loss of Rubicon ameliorates doxorubicin-induced cardiotoxicity through enhancement of mitochondrial quality

Xiaoyun Liu,Shasha Zhang,Lin An,Jian Wu,Xiaowen Hu,Shuaiwei Lai,Haniya Mazhar,Yunzeng Zou,Lin He,Hongxin Zhu

International Journal of Cardiology（2019）

引用 66|浏览5

暂无评分

摘要

•Loss of Rubicon ameliorates DOX-induced cardiotoxicity.•DOX-induced mitochondrial damage in the heart is attenuated by Rubicon deficiency.•Loss of Rubicon mitigates DOX-induced impairment of autophagic flux, mitophagy and mitochondrial dynamics in the heart.

查看译文

关键词

Rubicon,Doxorubicin,Cardiotoxicity,Autophagy,Mitophagy,Mitochondrial dynamics

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要