Estimation of the α/β ratio of non-small cell lung cancer treated with stereotactic body radiotherapy.

Radiotherapy and Oncology(2020)

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摘要
•The goal was to infer the α/β ratio in SBRTs for early stage NSCLC.•We conducted a tumor control probability modeling study of almost 1300 SBRT cases.•The LQ formalism appears valid for converting between SBRT schedules.•Our results support most probable α/β estimates in the range 12–16 Gy.•However, large uncertainties do not rule out α/β = 10 Gy.
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关键词
Radiobiology,SBRT,NSCLC,Tumor control probability,Linear-quadratic model
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