The clinical impact of family history of cancer in female never-smoker lung adenocarcinoma

Youngjoo Lee,Jae Hyun Jeon,Sung-Ho Goh,Hanseong Roh,Ji-Young Yun,Nak-Jung Kwon,Jin Ho Choi,Hee Chul Yang,Moon Soo Kim,Jong Mog Lee,Geon Kook Lee,Ji-Youn Han

Lung Cancer（2019）

引用 7|浏览22

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摘要

•Family history of cancer is related to distinct subtypes of never smoker lung cancer.•ALK/ROS1/RET fusions are enriched in patients with family history of nonlung cancer.•EGFR mutations are enriched in patients with family history of lung cancer.•Family history of nonlung cancer is associated with poor prognosis after operation.

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关键词

Never smoker,Non-small-cell lung cancer,Prognosis,Family history,EGFR,ALK

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