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Design of Selective PI3Kδ Inhibitors Using an Iterative Scaffold-Hopping Workflow

Xavier Fradera,Joey L. Methot,Abdelghani Achab,Matthew Christopher,Michael D. Altman,Hua Zhou,Meredeth A. McGowan,Sam D. Kattar,Kevin Wilson,Yudith Garcia,Martin A. Augustin,Charles A. Lesburg,Sanjiv Shah,Peter Goldenblatt,Jason D. Katz

Bioorganic & Medicinal Chemistry Letters（2019）

引用 17|浏览42
关键词
PI3K delta,Scaffold-hopping,Structure-based drug design,Oxindole
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