Lymph node infiltration, parallel metastasis and treatment success in breast cancer.

Jutta Engel,Wilko Weichert,Andreas Jung,Rebecca Emeny,Dieter Hölzel

The Breast（2019）

引用 14|浏览5

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摘要

•Data on the number of positive LNs as a function of tumor diameter in HR + breast cancer.•Shows a uniform, accelerating LN infiltration by growing primary tumors.•Supports a parallel MET initiation, not caused by positive lymph nodes.•Provides estimates of MET in negative LNs as a function of tumor diameter.•Can explain effects and limits of adjuvant therapies.

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关键词

Invasive breast cancer,Infiltration process,Positive lymph nodes,Metastasis,Recurrence score,Survival

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