Exposure to low doses of oxybenzone during perinatal development alters mammary gland morphology in male and female mice

Reproductive Toxicology(2020)

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摘要
•Perinatal oxybenzone exposure alters anogenital index in a dose specific manner.•Oxybenzone reduces the size and complexity of the male mammary gland before puberty.•Oxybenzone induces modest changes in female mammary gland morphology at puberty.•Perinatal oxybenzone exposure induces alveolar bud development in adult females.•Oxybenzone alters hormone receptor expression and proliferation in the mammary gland.
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关键词
2-hydroxy-4methoxybenzophenone,Endocrine disruptor,Sunscreen,Xenoestrogen,Anogenital distance
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