Spread of NDM-5 and OXA-181 carbapenemase-producing Escherichia coli in Chad.

Oumar Ouchar Mahamat,Manon Lounnas,Mallorie Hide,Abelsalam Tidjani,Julio Benavides, Abibatou Diack, Calèbe Somasse, Kadidja Gamougam,Christian Carrière,Dominique Decré,Anne-Laure Bañuls,Hélène Jean-Pierre,Yann Dumont,Fabrice Compain,Sylvain Godreuil

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY（2019）

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摘要

We detected for the first time bla(NDM-5) and bla(OXA-181) in Escherichia coli isolates from hospitalized patients and healthy volunteers in Chad. These resistance genes were located on IncX3 and IncF plasmids. Despite the large diversity of E. coli clones, the identified resistant intestinal isolates belonged mainly to the same sequence type.

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关键词

carbapenemases,Escherichia coli,clinical samples,fecal carriage prevalence,Chad

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